Distribution of regression slopes for metabolic cycling conditions of Tu et al. 2005. In our expression data, Tu et al.'s "most periodic" genes during metabolic cycling (their Table 2, black line) are induced as growth rate increases, as are their mitochondrial and cytoplasmic ribosomal clusters (their Supplemental Tables S1 and S3, green and blue lines). Peroxisomal genes (their Supplemental Table S2, red line) respond bimodally to growth rate, with the majority showing negative correlation and the minority not responding substantially to growth rate (including several stress response genes).
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